For 8 days in 1986, the earth passed through the tail of a mysterious Rea-M rogue comet. During that time, machines on earth suddenly come to life and terrorize their human creators. A small group of people in a truck stop, surrounded by "alive" semi-trailers, set out to stop the machines before the machines stop them.

In 1941, New York intellectual playwright Barton Fink comes to Hollywood to write a Wallace Beery wrestling picture. Staying in the eerie Hotel Earle, Barton develops severe writer's block. His neighbor, jovial insurance salesman Charlie Meadows, tries to help, but Barton continues to struggle as a bizarre sequence of events distracts him even further from his task.

A talented young man can't get an executive position without rising through the ranks, so he comes up with a shortcut, which also benefits his love life.